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Scans of mummies from four geographical regions across a period of 4,000 years suggest that atherosclerosis was more common in anc"...
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Platelet inhibition by Plavix is irreversible and will last for the life of the platelet. Overdose following clopidogrel administration may result in bleeding complications. A single oral dose of clopidogrel at 1500 or 2000 mg/kg was lethal to mice and to rats and at 3000 mg/kg to baboons. Symptoms of acute toxicity were vomiting, prostration, difficult breathing, and gastrointestinal hemorrhage in animals.
Based on biological plausibility, platelet transfusion may restore clotting ability.
Last reviewed on RxList: 12/30/2013
This monograph has been modified to include the generic and brand name in many instances.
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