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- Clinician Information:
Plavix Patient Information including If I Miss a Dose
In this Article
- What is clopidogrel (Plavix)?
- What are the possible side effects of clopidogrel (Plavix)?
- What is the most important information I should know about clopidogrel (Plavix)?
- What should I discuss with my healthcare provider before taking clopidogrel (Plavix)?
- How should I take clopidogrel (Plavix)?
- What happens if I miss a dose (Plavix)?
- What happens if I overdose (Plavix)?
- What should I avoid while taking clopidogrel (Plavix)?
- What other drugs will affect clopidogrel (Plavix)?
- Where can I get more information?
What happens if I miss a dose (Plavix)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Plavix)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include vomiting, feeling exhausted or short of breath, and blood in your stools or vomit.
What should I avoid while taking clopidogrel (Plavix)?
While you are taking clopidogrel, do not take aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) without your doctor's advice. NSAIDs include ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), meloxicam (Mobic), and others.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
Avoid drinking alcohol. It may increase your risk of bleeding in your stomach or intestines.
What other drugs will affect clopidogrel (Plavix)?
Tell your doctor about all other medicines you use to prevent blood clots, including:
- abciximab (ReoPro);
- dalteparin (Fragmin);
- drotrecogin alfa (Xigris);
- enoxaparin (Lovenox);
- eptifibatide (Integrilin);
- fondaparinux (Arixtra);
- ticlopidine (Ticlid);
- tinzaparin (Innohep);
- tirofiban (Aggrastat);
- urokinase (Abbokinase); and
- warfarin (Coumadin).
Tell your doctor about all other medicines you use, especially:
- armodafanil (NuVigil) or modafanil (Provigil);
- fluoxetine (Prozac) or fluvoxamine (Luvox);
- gemfibrozil (Lopid);
- isoniazid (Rifamate, Rifater);
- a cancer medication such as dasatinib (Sprycel), letrozole (Femara), ibritumomab (Zevalin), or tositumomab (Bexxar);
- certain stomach acid reducers, such as cimetidine (Tagamet), esomeprazole (Nexium), dexlansoprazole (Kapidex), lansoprazole (Prevacid), omeprazole (Prilosec, Prilosec OTC, Zegerid), pantoprazole (Protonix), or rabeprazole (AcipHex);
- an antifungal medication such as fluconazole (Diflucan), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), or voriconazole (Vfend);
- HIV medications such as delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), etravirine (Intelence), or tipranavir (Aptivus); or
- seizure medication such as felbamate (Felbatol) or oxcarbamazepine (Trileptal).
This list is not complete and other drugs may interact with clopidogrel. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about clopidogrel.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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Additional Plavix Information
- Plavix Drug Interactions Center: clopidogrel oral
- Plavix Side Effects Center
- Plavix FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
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