Brand Names: Plendil

Generic Name: felodipine (Pronunciation: fe LOE di peen)

• What is felodipine (Plendil)?
• What are the possible side effects of felodipine (Plendil)?
• What is the most important information I should know about felodipine (Plendil)?
• What should I discuss with my healthcare provider before taking felodipine (Plendil)?
• How should I take felodipine (Plendil)?
• What happens if I miss a dose (Plendil)?
• What happens if I overdose (Plendil)?
• What should I avoid while taking felodipine (Plendil)?
• What other drugs will affect felodipine (Plendil)?
• Where can I get more information?

What is felodipine (Plendil)?

Felodipine is in a class of drugs called calcium channel blockers. Felodipine relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Felodipine is used to treat hypertension (high blood pressure).

Felodipine may also be used for purposes other than those listed in this medication guide.

Felodipine 10 mg-MUT

round, brown, imprinted with MP 773

Felodipine 10 mg-MYL

round, blue, imprinted with F13, M

Felodipine 2.5 mg-MUT

round, green, imprinted with MP 771

Felodipine 2.5 mg-MYL

round, white, imprinted with F11, M

Felodipine 5 mg-MUT

round, orange, imprinted with MP 772

Felodipine 5mg-MYL

round, yellow, imprinted with F12, M

Plendil 10 mg

round, pink, imprinted with PLENDIL, 452

Plendil 2.5 mg

round, green, imprinted with PLENDIL, 450

Plendil 5 mg

round, pink, imprinted with PLENDIL, 451

What are the possible side effects of felodipine (Plendil)?

If you experience any of the following serious side effects, stop taking felodipine and contact your doctor immediately or seek emergency medical treatment:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• unusually fast or slow heartbeat;
• chest pain;
• severe dizziness or fainting;
• abnormal behavior or psychosis;
• jaundice (yellowing of the skin or eyes), or
• swelling of the legs, ankles, or face.

Other, less serious side effects may be more likely to occur. Continue to take felodipine and talk to your doctor if you experience

• fatigue or tiredness;
• headache;
• insomnia or difficulty sleeping;
• swelling of your gums;
• nausea or diarrhea;
• increased or difficult urination;
• muscle or joint discomfort; or
• flushing (redness).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about felodipine (Plendil)?

Do not stop taking felodipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.

Brush and floss your teeth regularly as directed by your dentist. Rarely, swelling of the gums may be a side effect from treatment with felodipine. Proper oral hygiene may alleviate these symptoms.

Do not crush, chew, or break the tablets. Swallow them whole.

Grapefruit and grapefruit juice may interact with felodipine. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.