Pletal (Cilostazol) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

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Peripheral Vascular Disease »

What is peripheral vascular disease?

Peripheral vascular disease (PVD) refers to diseases of the blood vessels (arteries and veins) located outside the heart and brain. While there are many causes of peripheral vascular disease, doctors commonly use the term peripheral vascular disease to refer to peripheral artery disease (peripheral arterial disease, PAD), a condition that develops when the arteries that supply blood to the internal organs, arms, and legs become completely or partially blocked as a result of atherosclerosis.

What is atherosclerosis?

Atherosclerosis is a gradual process whereby hard cholesterol substances (plaques) are deposited in the walls of the arteries. Cholesterol plaques cause hardening of the artery walls and narrowing of the inner channel (lumen) of the artery. The atherosclerosis process begins early in life (as early as teens in some people). When atherosclerosis is mild an...

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Pletal Patient Information including If I Miss a Dose

What happens if I miss a dose (Pletal)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Pletal)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include a severe headache, diarrhea, feeling light-headed, fainting, and fast or uneven heartbeats.

What should I avoid while taking cilostazol (Pletal)?

Grapefruit and grapefruit juice may interact with cilostazol. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

What other drugs will affect cilostazol (Pletal)?

Before taking cilostazol, tell your doctor if you are using any of the following drugs:

clopidogrel (Plavix);
omeprazole (Prilosec, Zegerid) or esomeprazole (Nexium);
erythromycin (E.E.S., Ery-Tab, E-Mycin, Erythrocin) or clarithromycin (Biaxin);
ketoconazole (Nizoral), fluconazole (Diflucan), or itraconazole (Sporanox);
diltiazem (Cardizem, Tiazac); or
fluvoxamine (Luvox), fluoxetine (Prozac), sertraline (Zoloft), or nefazodone (Serzone).

This list is not complete and there may be other drugs that can interact with cilostazol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has more information about cilostazol.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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