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Pneumovax

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Pneumovax

PNEUMOVAX®23
(pneumococcal) Vaccine Polyvalent

Pneumovax

DRUG DESCRIPTION

PNEUMOVAX 23 (Pneumococcal Vaccine Polyvalent) is a sterile, liquid vaccine for intramuscular or subcutaneous injection. It consists of a mixture of highly purified capsular polysaccharides from the 23 most prevalent or invasive pneumococcal types of Streptococcus pneumonias, including the six serotypes that most frequently cause invasive drug-resistant pneumococcal infections among children and adults in the United States.1 (See Table 1.) The 23-valent vaccine accounts for at least 90% of pneumococcal blood isolates and at least 85% of all pneumococcal isolates from sites which are generally sterile as determined by ongoing surveillance of U.S. data.2

PNEUMOVAX (pneumococcal vaccine polyvalent) 23 is manufactured according to methods developed by the Merck Research Laboratories. Each 0.5 ml dose of vaccine contains 25 (ig of each polysaccharide type in isotonic saline solution containing 0.25% phenol as a preservative.

Table 1: 23 Pneumococcal Capsular Types Included in PNEUMOVAX (pneumococcal vaccine polyvalent) 23

Nomenclature Pneumococcal Types
Danish 1 2 3 4 5 6B** 7F 8 9N 9V** 10A 11A 12F 14** 15B 17F 18C 19F** 19A** 20 22F 23F** 33F
** These serotypes most frequently cause drug-resistant pneumococcal infections1

What are the precautions when taking pneumococcal vaccine polyvalent (Pneumovax)?

Before receiving this vaccine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as the preservative phenol, latex or dry natural rubber in the vial stopper), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: your vaccination/immunization history, recent illness/fever.

This vaccine is not recommended for use in children younger than 2 years.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk....

Read All Potential Precautions of Pneumovax »

REFERENCES

What are the precautions when taking pneumococcal vaccine polyvalent (Pneumovax)?

Before receiving this vaccine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as the preservative phenol, latex or dry natural rubber in the vial stopper), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: your vaccination/immunization history, recent illness/fever.

This vaccine is not recommended for use in children younger than 2 years.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk....

Read All Potential Precautions of Pneumovax »

1. Centers for Disease Control and Prevention. Prevention of Pneumococcal Disease. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 1997; 46 (No. RR-8): 1-25. Available from: http://www.cdc.gov/mmwr/PDF/rr/rr4608.pdf

What are the precautions when taking pneumococcal vaccine polyvalent (Pneumovax)?

Before receiving this vaccine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as the preservative phenol, latex or dry natural rubber in the vial stopper), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: your vaccination/immunization history, recent illness/fever.

This vaccine is not recommended for use in children younger than 2 years.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk....

Read All Potential Precautions of Pneumovax »

2. Robbins, J.B.; Lee, C.J.; Schiffman, G.; Austrian, R.; Henrichsen, J.; Makela, P.M.; Broome, C.V.; Facklam, R.R.; Tiesjema, R.H.; Rastogi, S.C.: Considerations for formulating the second-generation pneumococcal capsular polysaccharide vaccine with emphasis on the cross-reactive types within groups, J. Infect. Dis. 148:1136-1159,1983.

What are the precautions when taking pneumococcal vaccine polyvalent (Pneumovax)?

Before receiving this vaccine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as the preservative phenol, latex or dry natural rubber in the vial stopper), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: your vaccination/immunization history, recent illness/fever.

This vaccine is not recommended for use in children younger than 2 years.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk....

Read All Potential Precautions of Pneumovax »

Last reviewed on RxList: 12/7/2010
This monograph has been modified to include the generic and brand name in many instances.

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