How does Policosanol work?
Policosanol seems to decrease cholesterol production in the liver and to increase the break down of LDL (low-density lipoprotein or "bad") cholesterol. It also decreases the stickiness of particles in the blood known as platelets, which might help reduce blood clots.
Are there safety concerns?
Policosanol appears to be safe for most people when used in doses of 10-80 mg per day for up to two years. It can cause skin redness and rash, migraines, insomnia or drowsiness, irritability, dizziness, upset stomach, increased appetite, trouble urinating, weight loss, nose and gum bleeds, and other side effects.
Do not take policosanol if:
- You are pregnant or breast-feeding.
- You are scheduled for surgery in the next two weeks. Policosanol might increase the risk of bleeding.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.