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(prednisolone acetate, neomycin sulfate, polymyxin B sulfate) Ophthalmic Suspension, USP Sterile
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Details with Side Effects
POLY-PRED® (prednisolone acetate, neomycin sulfate, polymyxin B sulfate ophthalmic suspension, USP) is a topical anti-inflammatory/anti-infective combination product for ophthalmic use with a pH of 5.0 - 7.0 and an osmolality of 260-340 mOsm/kg.
Prednisolone acetate: 11β, 17, 21-Trihydroxypregna-1, 4-diene-3, 20-dione 21-acetate.
Neomycin sulfate is the sulfate salt of neomycin B and neomycin C which are produced by the growth of Streptomyces fradiae (Fam. Streptomycetaceae). It has a potency equivalent to not less than 600 micrograms per milligram of neomycin base, calculated on an anhydrous basis.
Polymyxin B sulfate is the sulfate salt of polymyxin B1 and polymyxin B2 which are produced by the growth of Bacillus polymyxa (Prazmowski) Migula (Fam. Bacillaceae). It has a potency of not less than 6,000 polymyxin B units per milligram, calculated on an anhydrous basis.
Contains: Actives: prednisolone acetate (microfine suspension) 0.5%, neomycin sulfate equivalent to 0.35% neomycin base, polymyxin B sulfate 10,000 units/mL. Inactives: polysorbate 80; polyvinyl alcohol; propylene glycol; purified water; sodium acetate; and thimerosal 0.001% (preservative). The pH range is 5.0 - 7.0.
What are the possible side effects of neomycin, polymyxin B, and prednisolone ophthalmic (Poly Pred)?
Serious side effects are not expected with this medication.
Some burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...
What are the precautions when taking prednisolone,neomycin and polymyxin b (Poly-Pred)?
Before using this medication, tell your doctor or pharmacist if you are allergic to neomycin, polymyxin, or prednisolone; or to aminoglycoside antibiotics (e.g., gentamicin, tobramycin); or to corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like thimerosal), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: other eye problems (e.g., glaucoma).
After you apply this drug, your vision may become temporarily unstable. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform...
Last reviewed on RxList: 2/19/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Poly-Pred Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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