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Polymyxin B

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Polymyxin B

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Polymyxin B Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Polymyxin B (polymyxin b sulfate) is used to treat bacterial infections such as urinary tract infections, meningitis, blood infections, and eye infections. It is an antibiotic. This medication is available in generic form. Common side effects include pain, redness, and swelling at the injection site, or temporary eye stinging/burning/redness/itchiness or temporary blurred vision if used as eye drops.

Polymyxin B dose is determined by a doctor, based on the condition being treated. It may be injected into a vein, muscle, or the spinal fluid or into the area around the eye (subconjunctival sac). It can also be prepared as eye drops. Polymyxin B may interact with other drugs that can harm the kidneys or nerves (e.g., cisplatin, colistin, high-dose aspirin, aminoglycosides such as amikacin, gentamicin, tobramycin, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen or naproxen). Tell your doctor all medications you are taking. During pregnancy, Polymyxin B should be used only when prescribed. It is unknown if this medication passes into breast milk when used in the eye. It is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

Our Polymyxin B (polymyxin b sulfate) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Polymyxin B Prescribing Information: Indications & Dosage

Polymyxin B Structural Formula Illustration

Acute Infections Caused by Susceptible Strains of Pseudomonas aeruginosa.

Polymyxin B (polymyxin b sulfate) sulfate is a drug of choice in the treatment of infections of the urinary tract, meninges, and bloodstream caused by susceptible strains of Ps. aeruginosa. It may also be used topically and subconjunctivally in the treatment of infections of the eye caused by susceptible strains of Ps. aeruginosa.

It may be indicated in serious infections caused by susceptible strains of the following organisms, when less potentially toxic drugs ar...

Read the complete drug monograph for Polymyxin B »

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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