May 1, 2017
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Potiga Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking ezogabine (Potiga)?

You should not use ezogabine if you are allergic to it.

To make sure you can safely use ezogabine, tell your doctor if you have any of these other conditions:

  • kidney disease;
  • liver disease;
  • an enlarged prostate;
  • urination problems;
  • heart disease or a heart rhythm disorder;
  • a history of depression, mental illness, or suicidal thoughts or actions;
  • a personal or family history of Long QT syndrome; or
  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).

Ezogabine may be habit forming and should be used only by the person it was prescribed for. Never share ezogabine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

FDA pregnancy category C. It is not known whether ezogabine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of ezogabine on the baby.

It is not known whether ezogabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using ezogabine.

Do not give this medication to anyone under 18 years old without medical advice.

How should I take ezogabine (Potiga)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Ezogabine is usually taken 3 times each day. Follow your doctor's instructions.

You may take ezogabine with or without food.

Do not crush, chew, break, or dissolve a ezogabine tablet. Swallow it whole.

Do not stop using ezogabine without first talking to your doctor, even if you feel fine. You may have increased seizures if you stop using ezogabine suddenly. You may need to use less and less before you stop the medication completely.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using ezogabine.

Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Ezogabine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side Effects Centers

Additional Potiga Information

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Find tips and treatments to control seizures.