Prandimet (Repaglinide and Metformin HCl Tablets) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

Prandimet

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Diabetes is a chronic condition associated with abnormally high levels of sugar (glucose) in the blood.
Insulin produced by the pancreas lowers blood glucose.
Absence or insufficient production of insulin causes diabetes.
The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent).
Symptoms of diabetes include increased urine output, thirst and hunger as well as fatigue.
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Prandimet

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Prandimet Patient Information including If I Miss a Dose

What happens if I miss a dose (Prandimet)?

Take the missed dose as soon as you remember, but only if you are getting ready to eat a meal. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Prandimet)?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of metformin may cause a life-threatening condition called lactic acidosis. Get emergency medical help if you have any of these symptoms of lactic acidosis: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired.

Overdose symptoms may also include diarrhea, or signs of low blood sugar, such as hunger, headache, confusion, irritability, trouble concentrating, drowsiness, dizziness, weakness, blurred vision, tremors, sweating, nausea, fast heartbeat, and seizure (convulsions).

What should I avoid while taking metformin and repaglinide (Prandimet)?

Avoid drinking alcohol while taking metformin and repaglinide. Alcohol lowers blood sugar and may increase the risk of lactic acidosis while you are taking this medicine.

What other drugs will affect metformin and repaglinide (Prandimet)?

You should not use metformin and repaglinide together with NPH insulin (such as isophane insulin).

The following drugs can interact with metformin and repaglinide. Tell your doctor if you are using any of these:

digoxin (digitalis, Lanoxin);
morphine (Kadian, MS Contin, Oramorph, and others);
quinine (Qualaquin);
ranitidine (Zantac);
an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), ketoconazole (Nizoral), rifampin (Rifadin, Rifater, Rifamate), trimethoprim (Bactrim, Septra, Cotrim), vancomycin (Vancocin), and others;
a diuretic such as amiloride (Midamor) or triamterene (Dyrenium); or
heart rhythm medication such as procainamide (Procan, Procanbid, Pronestyl) or quinidine (Quinaglute, Quinidex, Quin-Release).

This list is not complete and there may be other drugs that can interact with metformin and repaglinide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about metformin and repaglinide.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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