Brand Names: Prandin

Generic Name: repaglinide (oral) (Pronunciation: re PAG li nide)

• What is repaglinide (Prandin)?
• What are the possible side effects of repaglinide (Prandin)?
• What is the most important information I should know about repaglinide (Prandin)?
• What should I discuss with my doctor before taking repaglinide (Prandin)?
• How should I take repaglinide (Prandin)?
• What happens if I miss a dose (Prandin)?
• What happens if I overdose (Prandin)?
• What should I avoid while taking repaglinide (Prandin)?
• What other drugs will affect repaglinide (Prandin)?
• Where can I get more information?

What is repaglinide (Prandin)?

Repaglinide is an oral diabetes medicine that helps control blood sugar levels. This medication lowers blood sugar by causing the pancreas to produce insulin.

Repaglinide is used together with diet and exercise to treat type 2 (non-insulin dependent) diabetes. Other diabetes medicines are sometimes used in combination with repaglinide if needed.

Repaglinide may also be used for other purposes not listed in this medication guide.

Prandin 0.5 mg

round, white, imprinted with LOGO BULL

Prandin 1 mg

round, yellow, imprinted with LOGO BULL

Prandin 2 mg

round, peach, imprinted with LOGO BULL

What are the possible side effects of repaglinide (Prandin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• seizure (convulsions);
• severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
• pale or yellowed skin, dark colored urine, fever, confusion or weakness; or
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.

Less serious side effects may include:

• runny or stuffy nose, sneezing, cough, cold or flu symptoms;
• diarrhea, nausea;
• back pain, headache;
• dizziness;
• blurred vision;
• joint pain; or
• temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about repaglinide (Prandin)?

Do not use this medication if you are allergic to repaglinide, if you have type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). You should not use repaglinide together with gemfibrozil (Lopid) or NPH insulin (such as isophane insulin).

Take care not to let your blood sugar get too low, causing hypoglycemia. You may have hypoglycemia if you skip a meal, exercise too long, drink alcohol, or are under stress.

Know the signs of low blood sugar (hypoglycemia) and how to recognize them. Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. Severe hypoglycemia may cause loss of consciousness, seizures, or death. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection.

If your blood sugar gets too high (hyperglycemia), you may feel very thirsty or hungry. You may also urinate more than usual. Call your doctor right away if you have any symptoms of hyperglycemia.

Repaglinide is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.

It is important to take repaglinide regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.