Precedex (Dexmedetomidine hydrochloride) Drug Information: Medication Guide and Patient Information

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May 27, 2012

Precedex

Sleep Disorder Drugs »

Sleep disorder drugs (hypnotic and sedative drugs) overview

Insomnia, a disorder of sleep, occurs occasionally in most people but usually lasts only a few days. The body then "corrects" itself naturally, and people return to a normal pattern of sleep. Insomnia may be short-term (less than three weeks) or chronic, lasting longer than three weeks. Contributing factors include, but are not limited to, poor sleeping habits, stress, jet lag, medications, disease, and depression. Chronic insomnia may warrant the use of sedative/hypnotics medications; however, it is important that the treating physician perform a complete diagnostic evaluation as well as take medication and substance abuse histories, to exclude secondary insomnia due to other conditions.

Hypnotics/sedatives medications (henceforth referred to as hypnotics) work, in general, by increasing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter in the brain. Neuro...

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Precedex

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PATIENT INFORMATION

Precedex (dexmedetomidine hydrochloride) is indicated for short-term intravenous sedation. Dosage must be individualized and titrated to the desired clinical effect. Blood pressure, heart rate and oxygen levels will be monitored both continuously during the infusion of Precedex (dexmedetomidine hydrochloride) and as clinically appropriate after discontinuation. .

When Precedex (dexmedetomidine hydrochloride) is infused for more than 6 hours, patients should be informed to report nervousness, agitation, and headaches that may occur for up to 48 hours. .
Additionally, patients should be informed to report symptoms that may occur within 48 hours after the administration of Precedex (dexmedetomidine hydrochloride) such as: weakness, confusion, excessive sweating, weight loss, abdominal pain, salt cravings, diarrhea, constipation, dizziness or light-headedness.

Last reviewed on RxList: 11/15/2010
This monograph has been modified to include the generic and brand name in many instances.