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Prednisolone

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Prednisolone

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Prednisolone

Prednisolone Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Prednisolone is an adrenocortical steroid used for multiple conditions including endocrine disorders, rheumatic disorders, collagen diseases, skin diseases, allergies, eye diseases, respiratory diseases, blood disorders, cancers, edematous states, gastrointestinal diseases, and nervous system disorders, among others. The brand name of this medication is discontinued, but generic versions may be available. Common side effects include infections, excess stomach acid, insomnia, hunger, and nervousness.

The initial dosage of prednisolone varies from 5 mg to 60 mg per day depending on the disease being treated. Prednisolone may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, prednisolone should be used only if prescribed. Consult your doctor before breastfeeding.

Our Prednisolone Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Prednisolone FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Fluid and Electrolyte Disturbances

Sodium retention. Fluid retention. Congestive heart failure in susceptible patients. Potassium loss. Hypokalemic alkalosis. Hypertension.

Musculoskeletal

Muscle weakness. Steroid myopathy. Loss of muscle mass. Osteoporosis. Vertebral compression fractures. Aseptic necrosis of femoral and humeral heads. Pathologic fracture of long bones.

Gastrointestinal

Peptic ulcer with possible perforation and hemorrhage. Pancreatitis. Abdominal distention. Ulcerative esophagitis.

Dermatologic

Impaired wound healing. Thin fragile skin. Petechiae and ecchymoses. Facial erythema. Increased sweating. May suppress reactions to skin tests.

Neurological

Convulsions. Increased intracranial pressure with papilledema (pseudotumor cerebri) usually after treatment. Vertigo. Headache.

Endocrine

Menstrual irregularities. Development of Cushingoid state. Suppression of growth in children. Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery, or illness. Decreased carbohydrate tolerance. Manifestations of latent diabetes mellitus. Increased requirements for insulin or oral hypoglycemic agents in diabetics.

Ophthalmic

Posterior subcapsular cataracts. Increased intraocular pressure. Glaucoma. Exophthalmos.

Metabolic

Negative nitrogen balance due to protein catabolism.

Read the entire FDA prescribing information for Prednisolone (Prednisolone Tablets) »

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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