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Pregnyl Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Pregnyl (chorionic gonadotropin) is used to cause ovulation and to treat infertility in women, and to increase sperm count in men. Human chorionic gonadotropin (HCG) is also used in young boys when their testicles have not dropped down into the scrotum normally. This can be caused by a pituitary gland disorder. HCG is a hormone. Common side effects include headache, restlessness, tiredness, or pain at injection site.
The dosage regimen of Pregnyl depends on the condition being treated, the age and weight of the patient, and the physician's preference. There may be other drugs that can interact with Pregnyl. Tell your doctor about all the prescription and over-the-counter medications and supplements you use. Pregnyl must not be used during pregnancy. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
Our Pregnyl (chorionic gonadotropin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Pregnyl in Detail - Patient Information: Side Effects
Stop using HCG and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these signs of a blood clot: pain, warmth, redness, numbness, or tingling in your arm or leg; confusion, extreme dizziness, or severe headache.
Some women using this medicine have developed a condition called ovarian hyperstimulation syndrome (OHSS), especially after the first treatment cycle. OHSS can be a life-threatening condition. Call your doctor right away if you have any of the following symptoms of OHSS:
- severe pelvic pain;
- swelling of the hands or legs;
- stomach pain and swelling;
- shortness of breath;
- weight gain;
- nausea or vomiting; or
- urinating less than normal.
This medication can cause early puberty in young boys. Call your doctor if a boy using this medicine shows early signs of puberty, such as a deepened voice, pubic hair growth, and increased acne or sweating.
Less serious side effects may include:
- feeling restless or irritable;
- mild swelling or water weight gain;
- breast tenderness or swelling; or
- pain, swelling, or irritation where the injection is given.
Read the entire detailed patient monograph for Pregnyl (Chorionic Gonadotropin)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Pregnyl Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling of the ankles/feet, mental/mood changes (e.g., depression, irritability), signs of early puberty in boys (e.g., facial/pubic hair, voice change, acne), pain/swelling of the breast (in boys).
For women, when this medication is used with menotropins to treat infertility, also tell your doctor immediately if this unlikely but serious side effect occurs: abdominal pain/pressure/swelling.
For women, when this medication is used with menotropins to treat infertility, seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, slurred speech, weakness on one side of the body, confusion.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, shortness of breath.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Pregnyl (Chorionic Gonadotropin)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Pregnyl FDA Prescribing Information: Side Effects
Hypersensitivity reactions, both localized and systemic in nature, have been reported.
Read the entire FDA prescribing information for Pregnyl (Chorionic Gonadotropin)
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