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Premarin

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Premarin

Overdosage
Contraindications

OVERDOSE

Overdosage of estrogen may cause nausea, vomiting, breast tenderness, abdominal pain, drowsiness and fatigue and withdrawal bleeding may occur in women. Treatment of overdose consists of discontinuation of PREMARIN therapy with institution of appropriate symptomatic care.

CONTRAINDICATIONS

PREMARIN therapy should not be used in individuals with any of the following conditions:

  1. Undiagnosed abnormal genital bleeding.
  2. Known, suspected, or history of breast cancer except in appropriately selected patients being treated for metastatic disease.
  3. Known or suspected estrogen-dependent neoplasia.
  4. Active DVT, PE, or a history of these conditions.
  5. Active arterial thromboembolic disease (for example, stroke and MI), or a history of these conditions.
  6. Known anaphylactic reaction or angioedema to PREMARIN tablets.
  7. Known liver dysfunction or disease.
  8. Known protein C, protein S, or antithrombin deficiency or other known thrombophilic disorders.
  9. Known or suspected pregnancy.

Last reviewed on RxList: 11/11/2011
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications
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