"March 14, 2013 -- Hormone replacement therapy is the most effective treatment for symptoms like hot flashes, and the benefits are likely to outweigh the risks, major medical societies say.
The statement was published in the April issue "...
Premarin Patient Information including How Should I Take
In this Article
- What are conjugated estrogens (Premarin)?
- What are the possible side effects of conjugated estrogens (Premarin)?
- What is the most important information I should know about conjugated estrogens (Premarin)?
- What should I discuss with my healthcare provider before taking conjugated estrogens (Premarin)?
- How should I take conjugated estrogens (Premarin)?
- What happens if I miss a dose (Premarin)?
- What happens if I overdose (Premarin)?
- What should I avoid while taking conjugated estrogens (Premarin)?
- What other drugs will affect conjugated estrogens (Premarin)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking conjugated estrogens (Premarin)?
Do not use conjugated estrogens if you have:
- a history of heart attack, stroke, or blood clot (especially in your lung or your lower body);
- abnormal vaginal bleeding that a doctor has not checked;
- a bleeding or blood-clotting disorder;
- liver disease; or
- any type of breast, uterine, or hormone-dependent cancer.
To make sure you can safely take conjugated estrogens, tell your doctor if you have any of these other conditions:
- high blood pressure, heart disease, or circulation problems;
- a personal or family history of stroke;
- kidney disease;
- hereditary angioedema;
- epilepsy or other seizure disorder;
- underactive thyroid;
- high cholesterol or triglycerides;
- high or low levels of calcium in your blood;
- systemic lupus erythematosus (SLE); or
- gallbladder disease.
Conjugated estrogens increase your risk of developing endometrial hyperplasia, a condition that may lead to cancer of the uterus. Taking progestins while using conjugated estrogens may lower this risk. If your uterus has not been removed, your doctor may prescribe a progestin for you to take while you are using conjugated estrogens.
Long-term use of conjugated estrogens may increase your risk of breast cancer, heart attack, stroke, or blood clot. Talk with your doctor about your individual risks before using conjugated estrogens long term, especially if you smoke or are overweight. Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment.
FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not use conjugated estrogens if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use effective birth control while you are using this medication.
Conjugated estrogens can pass into breast milk and may harm a nursing baby. This medicine may also slow breast milk production. Do not use if you are breast-feeding a baby.
Do not give this medication to anyone under 18 years old without the advice of a doctor.
How should I take conjugated estrogens (Premarin)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Conjugated estrogens are sometimes taken on a daily basis. For certain conditions, the medication is given in a cycle, such as 3 weeks on followed by 1 week off. Follow your doctor's instructions.
If you see what looks like part of a conjugated estrogen tablet in your stool, talk with your doctor.
Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using conjugated estrogens.
Use conjugated estrogens regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
To be sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. Your thyroid function may also need to be tested. Visit your doctor regularly.
If you need surgery or medical tests or if you will be on bed rest, you may need to stop using this medication for a short time. Any doctor or surgeon who treats you should know that you are taking conjugated estrogens.
Store at room temperature away from moisture and heat. Keep the medicine container tightly closed.
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