"The U.S. Food and Drug Administration today approved Brisdelle (paroxetine)to treat moderate to severe hot flashes (vasomotor symptoms) associated with menopause. Brisdelle, which contains the selective serotonin reuptake inhibitor paroxetine mes"...
Overdosage of estrogen plus progestin may cause nausea, vomiting, breast tenderness, abdominal pain, drowsiness and fatigue, and withdrawal bleeding may occur in women. Treatment of overdose consists of discontinuation of PREMPRO or PREMPHASE therapy with institution of appropriate symptomatic care.
PREMPRO or PREMPHASE therapy should not be used in women with any of the following conditions:
- Undiagnosed abnormal genital bleeding
- Known, suspected, or history of breast cancer
- Known or suspected estrogen-dependent neoplasia
- Active DVT, PE, or a history of these conditions
- Active arterial thromboembolic disease (for example, stroke and MI), or a history of these conditions
- Known anaphylactic reaction or angioedema to PREMPRO/PREMPHASE
- Known liver dysfunction or disease
- Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders
- Known or suspected pregnancy
Last reviewed on RxList: 2/21/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Prempro, Premphase Information
- Prempro, Premphase Drug Interactions Center: conj estrog-medroxyprogest ace oral
- Prempro, Premphase Side Effects Center
- Prempro, Premphase in detail including Side Effects and Drug Images
- Prempro, Premphase Overview including Precautions
- Prempro, Premphase FDA Approved Prescribing Information including Dosage
Prempro, Premphase - User Reviews
Prempro, Premphase User Reviews
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