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Prilosec

What is Helicobacter pylori?

Helicobacter pylori (H. pylori) is a bacterium that causes chronic inflammation of the inner lining of the stomach (gastritis) in humans. This bacterium also is considered as a common cause of ulcers worldwide; as many as 90% of people with ulcers have detectable organisms.

H. pylori infection is most likely acquired by ingesting contaminated food and water, and through person to person contact. In the United States, about 30% of the adult population is infected (50% of infected persons are infected by the age of 60), but the prevalence of infection is decreasing because there is increasing awareness about the infection, and treatment is common. About 50% of the world population is estimated to have detectable H. pylori in their gastrointestinal tract (GI tract, but stomach, mainly).

The infection is more common in crowded living conditions with poor sanitation. In countries with poor sanit...

Prilosec

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Prilosec Drug Center

Medical Editor: Melissa Conrad Stöppler, MD

Prilosec (omeprazole) is a drug belonging to the class known as proton pump inhibitors (PPIs). Proton pump inhibitors are used for the treatment of conditions such as ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome, which are all caused by stomach acid. For maximal efficacy, omeprazole tablets should be taken before meals, swallowed whole and should not be crushed, chewed or opened. Omeprazole is available in generic form. Side effects of Prilosec may include headache, nausea, diarrhea, stomach pain, or constipation

Prilosec potentially can increase the concentrations in blood of diazepam (Valium), warfarin (Coumadin), and phenytoin (Dilantin) by decreasing the elimination of these drugs by the liver. The absorption of certain drugs may be affected by stomach acidity, and, as a result, Prilosec and other PPIs that reduce stomach acid also reduce the absorption and concentration in blood of ketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin).

Our Prilosec Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Prilosec Prescribing Information: Indications & Dosage

Omeprazole Structural Formula Illustration

Duodenal Ulcer (adults)

PRILOSEC (omeprazole) is indicated for short-term treatment of active duodenal ulcer in adults. Most patients heal within four weeks. Some patients may require an additional four weeks of therapy.

PRILOSEC (omeprazole) in combination with clarithromycin and amoxicillin, is indicated for treatment of patients with H. pylori infection and duodenal ulcer disease (active or up to 1-year history) to eradicate H. pylori in adults.

PRILOSEC (omeprazole) in combination with clarithromycin is indicated for treatment of pa...

Read the complete drug monograph for Prilosec »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Prilosec Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Other less serious side effects are more likely to occur, such as:

  • stomach pain, gas;
  • nausea, vomiting, diarrhea; or
  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should k...

Read the complete patient information for Prilosec »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Prilosec Consumer Information: Uses

Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).

If you are self-treating with this medication, over-the-counter omeprazole products are used to treat frequent heartburn (occurring 2 or...

Read the complete consumer information for Prilosec »

What is Prilosec Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Prilosec - User Reviews

Prilosec User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Prilosec sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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