"Mutations in the TTN gene, which are commonly found in idiopathic dilated cardiomyopathy, also seem common in peripartum cardiomyopathyâ€”which may finally help explain why the latter condition occurs, new research suggests.
PROCARDIA® (nifedipine) is an antianginal drug belonging to a class of pharmacological agents, the calcium channel blockers. Nifedipine is 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2- nitrophenyl)-, dimethyl ester, C17H18N2O6, and has the structural formula:
Nifedipine is a yellow crystalline substance, practically insoluble in water but soluble in ethanol. It has a molecular weight of 346.3. PROCARDIA capsules are formulated as soft gelatin capsules for oral administration, each containing 10 mg nifedipine.
Inert ingredients in the formulation are: glycerin; peppermint oil; polyethylene glycol; soft gelatin capsules (which contain Yellow 6, and may contain Red Ferric Oxide and other inert ingredients); and water. The 10 mg capsules also contain saccharin sodium.
What are the possible side effects of nifedipine (Procardia)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- worsening angina;
- severe constipation and cramps, severe stomach pain or heartburn, coughing up blood;
- feeling like you might pass out;
- feeling short of breath, swelling in your hands or feet;
- fast or pounding heartbeats;
- numbness or tingly feeling;
- jaundice (yellowing of the skin or eyes);...
What are the precautions when taking nifedipine (Procardia)?
Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have a certain medical condition. Before using this medicine, consult your doctor or pharmacist if you have: certain heart problems (such as congestive heart failure, aortic stenosis).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, kidney problems.
Before having surgery, tell your doctor or dentist that you are taking this medication.
This drug may make you dizzy. Do not drive, use...
Last reviewed on RxList: 9/14/2016
This monograph has been modified to include the generic and brand name in many instances.
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