"Analysis of three biomarkers in the urine of kidney transplant recipients can diagnose — and even predict — transplant rejection, according to results from a clinical trial sponsored by the National Institute of Allergy and Infect"...
Prograf Patient Information Including Side Effects
Brand Names: Prograf
Generic Name: tacrolimus (oral and injection) (Pronunciation: ta KROE li mus)
- What is tacrolimus (Prograf)?
- What are the possible side effects of tacrolimus (Prograf)?
- What is the most important information I should know about tacrolimus (Prograf)?
- What should I discuss with my healthcare provider before taking tacrolimus (Prograf)?
- How should I take tacrolimus (Prograf)?
- What happens if I miss a dose (Prograf)?
- What happens if I overdose (Prograf)?
- What should I avoid while taking tacrolimus (Prograf)?
- What other drugs will affect tacrolimus (Prograf)?
- Where can I get more information?
What is tacrolimus (Prograf)?
Tacrolimus lowers your body's immune system. The immune system helps your body fight infections. The immune system can also fight or "reject" a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader.
Tacrolimus is used together with other medicines to prevent your body from rejecting a heart, liver, or kidney transplant.
Tacrolimus may also be used for purposes not listed in this medication guide.
Prograf 0.5 mg
capsule, yellow, imprinted with 0.5mg, LOGO 607
Prograf 1 mg
capsule, white, imprinted with 1 mg, 617
Prograf 5 mg
capsule, red, imprinted with 5mg, LOGO 657
What are the possible side effects of tacrolimus (Prograf)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- fever, chills, body aches, flu symptoms, sores in your mouth and throat;
- change in your mental state, problems with speech or walking, decreased vision (may start gradually and get worse quickly);
- pale or yellowed skin, dark colored urine, confusion or weakness;
- feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
- pain in the lower back or side, blood in your urine, pain or burning when you urinate;
- urinating less than usual or not at all;
- dry cough, cough with mucus or blood, sweating, wheezing, gasping for breath, chest pain;
- tremors (shaking), seizure (convulsions);
- high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
- low magnesium (jerky muscle movements, muscle weakness or limp feeling, slow reflexes);
- high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, shortness of breath, uneven heartbeats); or
- high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss).
Less serious side effects may include:
- nausea, stomach pain, diarrhea, constipation;
- sleep problems (insomnia); or
- swelling in your hands or feet.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Prograf (tacrolimus) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about tacrolimus (Prograf)?
Tacrolimus may increase your risk of developing serious infections, cancer, or transplant failure. Talk with your doctor about the risks and benefits of using this medication.
You will need regular medical tests to be sure tacrolimus is not causing harmful effects. Do not miss any follow up visits to your doctor for blood or urine tests. Avoid being near people who are sick or have infections.
Tacrolimus can harm your kidneys, and this effect is increased when you also use certain other medicines harmful to the kidneys. Before using tacrolimus, tell your doctor about all other medicines you use. Many other drugs (including some over-the-counter medicines) can be harmful to the kidneys.
Call your doctor right away if you have symptoms of a serious brain infection, such as a change in your mental state, problems with speech or walking, or decreased vision. These symptoms may start gradually and get worse quickly.
Additional Prograf Information
- Prograf Drug Interactions Center: tacrolimus oral
- Prograf Side Effects Center
- Prograf Overview including Precautions
- Prograf FDA Approved Prescribing Information including Dosage
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