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In this Article

• What is aldesleukin (Proleukin)?
• What are the possible side effects of aldesleukin (Proleukin)?
• What is the most important information I should know about aldesleukin (Proleukin)?
• What should I discuss with my healthcare provider before receiving aldesleukin (Proleukin)?
• How is aldesleukin given (Proleukin)?
• What happens if I miss a dose (Proleukin)?
• What happens if I overdose (Proleukin)?
• What should I avoid while receiving aldesleukin (Proleukin)?
• What other drugs will affect aldesleukin (Proleukin)?
• Where can I get more information?

What happens if I miss a dose (Proleukin)?

Call your doctor for instructions if you miss an appointment for your aldesleukin injection.

What happens if I overdose (Proleukin)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include confusion, hallucinations, fast or pounding heartbeats, chest pain, trouble walking or breathing, painful swelling in any part of your body, problems with vision or speech, urinating less than usual , or seizure (convulsions).

What should I avoid while receiving aldesleukin (Proleukin)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect aldesleukin (Proleukin)?

Before receiving aldesleukin, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, anxiety, or nausea and vomiting). They can add to sleepiness caused by aldesleukin.

Aldesleukin can be harmful to the kidneys, liver, heart, or bone marrow. These effects are increased when aldesleukin is used together with other medicines that can cause similar harmful effects. Tell your doctor about all other medications you are using, especially:

• an antibiotic taken by mouth or given in an IV;
• an antidepressant;
• antifungal medication;
• anti-malaria medications;
• antiviral medications, or medicines to treat HIV or AIDS;
• birth control pills or hormone replacement therapy;
• cholesterol-lowering medications;
• digoxin and other heart rhythm medication;
• heart or blood pressure medications;
• medicines to treat a bowel disorder;
• medicine to treat a psychiatric disorder;
• other cancer medications;
• pain or arthritis medicines (including aspirin, acetaminophen, gold compounds, or a non-steroidal anti-inflammatory drug [NSAID]);
• seizure medications;
• a steroid; or
• tuberculosis medications.

This list is not complete and there may be other drugs that can interact with aldesleukin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about aldesleukin.

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