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Prolixin Drug Center

Prolixin (fluphenazine) is used to treat symptoms of a certain type of mental/mood condition (schizophrenia). It is in a class of drugs called phenothiazines and is also referred to as a neuroleptic. The brand name Prolixin is discontinued and this medication is available in generic form only. Common side effects include drowsiness, lethargy, dizziness, nausea, loss of appetite, sweating, dry mouth, blurred vision, headache, or constipation.

Total daily dosage for adult psychotic patients may range initially from 2.5 to 10.0 mg and should be divided and given at six- to eight-hour intervals. Fluphenazine may interact with anticholinergics, dopamine agonists, guanadrel, guanethidine, lithium, sibutramine, isoniazid, theophylline, bupropion, tramadol, antihistamines, anti-anxiety drugs, anti-seizure drugs, medicine for sleep, muscle relaxants, narcotics, other psychiatric medicines, or tranquilizers. Check labels on all medicines (e.g., cold-and-cough products) because they may contain drowsiness-causing ingredients. Tell your doctor all medications you are taking. During pregnancy, fluphenazine should be used only when prescribed. Liver problems or birth defects may occur in infants exposed to this type of medication in the womb. Tell the doctor if you notice yellowing of the eyes/skin or dark urine in your infant. Babies born to mothers who have used this drug during the last 3 months of pregnancy may develop symptoms including muscle stiffness or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. If you notice these symptoms in your newborn during their first month, tell the doctor. Based on information for similar drugs, fluphenazine may pass into breast milk and may have undesirable effects on a nursing infant. Breast-feeding while using this medication is not recommended.

Our Prolixin (fluphenazine) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.