"The U.S. Food and Drug Administration yesterday approved Rixubis [Coagulation Factor IX (Recombinant)] for use in people with hemophilia B who are 16 years of age and older. Rixubis is indicated for the control and prevention of bleeding episodes"...
- Clinician Information:
Promacta Patient Information including If I Miss a Dose
In this Article
- What is eltrombopag (Promacta)?
- What are the possible side effects of eltrombopag (Promacta)?
- What is the most important information I should know about eltrombopag (Promacta)?
- What should I discuss with my health care provider before taking eltrombopag (Promacta)?
- How should I take eltrombopag (Promacta)?
- What happens if I miss a dose (Promacta)?
- What happens if I overdose (Promacta)?
- What should I avoid while taking eltrombopag (Promacta)?
- What other drugs will affect eltrombopag (Promacta)?
- Where can I get more information?
What happens if I miss a dose (Promacta)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Promacta)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose can cause slow heart rate, skin rash, or signs of a blood clot such as sudden numbness or weakness, sudden headache or confusion, problems with vision or speech, loss of balance, chest pain, sudden cough, and pain or swelling in one or both legs.
What should I avoid while taking eltrombopag (Promacta)?
Avoid taking other medications, including antacids or vitamin and mineral supplements, within 4 hours before or after you take eltrombopag.
What other drugs will affect eltrombopag (Promacta)?
Many drugs can interact with eltrombopag. Below is just a partial list. Tell your doctor if you are using:
- acetaminophen (Tylenol);
- acyclovir (Zovirax);
- atazanavir (Reyataz);
- birth control pills;
- fluvoxamine (Luvox);
- methotrexate (Rheumatrex, Trexall);
- penicillin G (Pfizerpen);
- rifampin (Rifadin, Rifater, Rifamate);
- ticlopidine (Ticlid);
- trimethoprim (Proloprim, Bactrim, Septra);
- zileuton (Zyflo);
- an antibiotic such as ciprofloxacin (Cipro), ofloxacin (Floxin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), and others;
- cholesterol-lowering medicines such as atorvastatin (Lipitor), fluvastatin (Lescol), gemfibrozil (Lopid), pravastatin (Pravachol), or rosuvastatin (Crestor);
- diabetes medication you take by mouth, such as nateglinide (Starlix), pioglitazone (Actos), repaglinide (Prandin), rosiglitazone (Avandia);
- heart rhythm medication such as amiodarone (Cordarone, Pacerone), mexiletine (Mexitil), propafenone (Rythmol), verapamil (Calan, Covera, Isoptin);
- narcotic pain medication such as fentanyl (Actiq, Duragesic), hydrocodone (Lortab, Vicodin, Vicoprofen), oxycodone (OxyContin, Endocet, Percocet), and others;
- an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others; or
- stomach acid reducers such as cimetidine (Tagamet), esomeprazole (Nexium), famotidine (Pepcid), omeprazole (Prilosec).
Where can I get more information?
Your doctor or pharmacist can provide more information about eltrombopag.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 3.01. Revision date: 4/6/2011.
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Additional Promacta Information
- Promacta Drug Interactions Center: eltrombopag oral
- Promacta Side Effects Center
- Promacta FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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