home > drugs a-z list > promethazine hcl and dextromethorphan hydrobromide syrup (promethazine and dextromethorphan) drug center > promethazine hcl and dextromethorphan hydrobromide syrup (promethazine and dextromethorphan) drug - medication guide and patient information

Patients should be advised to measure Promethazine HCl and Dextromethorphan Hydrobromide Syrup with an accurate measuring device. A household teaspoon is not an accurate measuring device and could lead to overdosage, especially when a half a teaspoon is measured. A pharmacist can recommend an appropriate measuring device and can provide instructions for measuring the correct dose.

Promethazine HCl and Dextromethorphan Hydrobromide (promethazine and dextromethorphan) Syrup may cause marked drowsiness or impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. Ambulatory patients should be told to avoid engaging in such activities until it is known that they do not become drowsy or dizzy from promethazine and dextromethorphan therapy. Pediatric patients should be supervised to avoid potential harm in bike riding or in other hazardous activities.

The concomitant use of alcohol or other central-nervous-system depressants, such as sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers, may enhance impairment (see WARNINGS - CNS Depression and PRECAUTIONS - DRUG INTERACTIONS).

Patients should be advised to report any involuntary muscle movements.

Avoid prolonged exposure to the sun.

Last reviewed on RxList: 5/15/2008
This monograph has been modified to include the generic and brand name in many instances.