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In this Article

• What is promethazine injection (Promethazine HCl Injection)?
• What are the possible side effects of promethazine injection (Promethazine HCl Injection)?
• What is the most important information I should know about promethazine injection (Promethazine HCl Injection)?
• What should I discuss with my health care provider before I receive promethazine injection (Promethazine HCl Injection)?
• How is promethazine injection given (Promethazine HCl Injection)?
• What happens if I miss a dose (Promethazine HCl Injection)?
• What happens if I overdose (Promethazine HCl Injection)?
• What should I avoid while receiving promethazine injection (Promethazine HCl Injection)?
• What other drugs will affect promethazine injection (Promethazine HCl Injection)?
• Where can I get more information?

What should I discuss with my health care provider before I receive promethazine injection (Promethazine HCl Injection)?

You should not use this medication if you are allergic to promethazine or to similar medicines such as chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), thioridazine (Mellaril), or trifluperazine (Stelazine).

If you have certain conditions, you may need a dose adjustment or special tests to safely receive this medication. Before you receive promethazine injection, tell your doctor if you are allergic to any drugs, or if you have:

• asthma, sleep apnea, or other breathing problems;
• epilepsy or other seizure disorder;
• a weak immune system (bone marrow depression);
• glaucoma;
• enlarged prostate or problems with urination;
• stomach ulcer or obstruction;
• heart disease or high blood pressure;
• liver disease;
• adrenal gland tumor (pheochromocytoma);
• low levels of calcium in your blood (hypocalcemia); or
• if you have ever had a serious side effect while using promethazine or any other phenothiazine.

FDA pregnancy category C. It is not known whether promethazine is harmful to an unborn baby. Before you receive this medication, tell your doctor if you are pregnant.

It is not known whether promethazine passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is promethazine injection given (Promethazine HCl Injection)?

Promethazine injection is given as an injection deep into a muscle. You will receive this injection in a clinic or hospital setting. This medication is usually given every 2 to 4 hours depending on the condition it is used for.

Promethazine injection is usually given for only a short time until no longer needed or until you can take promethazine by mouth.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you have recently received promethazine injection.