home > drugs a-z list > promethazine hcl suppositories (promethazine hydrochloride suppositories) drug center > promethazine hcl suppositories (promethazine hydrochloride suppositories) drug - consumer uses and warnings

Each rectal suppository contains 12.5 mg or 25 mg promethazine HCl with ascorbyl palmitate, silicon dioxide, white wax, and cocoa butter. Promethazine hydrochloride suppositories are for rectal administration only.

Promethazine HCl is a racemic compound; the empirical formula is C₁₇H₂₀N₂S•HCl and its molecular weight is 320.88.

Promethazine HCl, a phenothiazine derivative, is designated chemically as 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, monohydrochloride, (±)- with the following structural formula:

Promethazine HCl occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is freely soluble in water and soluble in alcohol.

Last reviewed on RxList: 6/13/2008
This monograph has been modified to include the generic and brand name in many instances.