Pronestyl (Procainamide) Drug Overview of Drug Interactions and Missed Dose for Patients and Caregivers at RxList

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May 27, 2012

Pronestyl

Abnormal Heart Rhythms (Heart Rhythm Disorders) »

How does the heart work?

The heart is a two stage electric pump whose job it is to circulate blood through the body. There is a group of cells that serve as an automatic pacemaker located in the atrium that generates an electrical current that spreads to the heart muscle cells to generate a coordinated squeeze, so that the pump can function.

The heart has four chambers, the right and left atria (singular= atrium) and the right and left ventricles. The right side of the heart pumps blood to the lungs while the left side pumps it to the rest of the body.

Blood from the body is collected in the right atrium and is pushed into the right ventricle with a small beat of the upper chamber of the heart. The right ventricle then pumps the blood to the lungs to pick up oxygen. They oxygen-rich blood returns to the left atrium where the small atrial beat pushes it to the left ventricle. The left ventricle is much thicker than the right because it needs t...

Read the Abnormal Heart Rhythms (Heart Rhythm Disorders) article »

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Pronestyl

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Pronestyl Consumer (continued)

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medications because very serious interactions may occur: ranolazine, disopyramide, ibutilide, propafenone, sertindole, droperidol, ziprasidone, bepridil, dofetilide, cisapride, mizolastine, pimozide, halofantrine.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting procainamide.

Many drugs besides procainamide and those listed above may affect the heart rhythm (QT prolongation), including amiodarone, quinidine, sotalol, flecainide, haloperidol, amitriptyline, levofloxacin, ciprofloxacin, macrolide antibiotics (such erythromycin), among others. Therefore, before using procainamide, report all medications you are currently using to your doctor or pharmacist.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: cimetidine, ranitidine, alcohol, trimethoprim, succinylcholine.

Certain drugs may interfere with lab blood tests for procainamide (lidocaine, meprobamate, propranolol). Tell laboratory personnel and all your doctors if you are taking these medications.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: sudden fast/pounding heartbeat, dizziness, fainting, confusion, nausea, vomiting.

NOTES: Do not share this medication with others.

Laboratory and/or medical tests (e.g., EKG, procainamide blood levels, blood counts, liver/kidney blood tests, blood antinuclear antibody) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).