"March 21, 2012 -- Researchers are zeroing in on a new potential cause of male pattern baldness, and their discovery may pave the way toward more effective and targeted treatments.
Male pattern baldness affects 80% of men younger than "...
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In clinical studies, single doses of finasteride up to 400 mg and multiple doses of finasteride up to 80 mg/day for three months did not result in adverse reactions. Until further experience is obtained, no specific treatment for an overdose with finasteride can be recommended.
Significant lethality was observed in male and female mice at single oral doses of 1500 mg/m² (500 mg/kg) and in female and male rats at single oral doses of 2360 mg/m² (400 mg/kg) and 5900 mg/m² (1000 mg/kg), respectively.
PROPECIA is contraindicated in the following:
- Pregnancy. Finasteride use is contraindicated in women when they are or may potentially be pregnant. Because of the ability of Type II 5α-reductase inhibitors to inhibit the conversion of testosterone to 5α-dihydrotestosterone (DHT), finasteride may cause abnormalities of the external genitalia of a male fetus of a pregnant woman who receives finasteride. If this drug is used during pregnancy, or if pregnancy occurs while taking this drug, the pregnant woman should be apprised of the potential hazard to the male fetus. [See WARNINGS AND PRECAUTIONS, Use In Specific Populations, HOW SUPPLIED/Storage and Handling and PATIENT INFORMATION.] In female rats, low doses of finasteride administered during pregnancy have produced abnormalities of the external genitalia in male offspring.
- Hypersensitivity to any component of this medication.
Last reviewed on RxList: 4/19/2012
This monograph has been modified to include the generic and brand name in many instances.
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