Propecia (Finasteride) Drug Information: Overdosage and Contraindications

Pill Identifier Search

May 27, 2012

Propecia

Hair Loss »

What are causes of hair loss?

There are many causes of scalp hair loss, and they do differ in men and women. This article will cover the common ones. Studies show that losing up to 100-150 hairs per day is normal. Human hair naturally grows in three phases: anagen, catagen, and telogen. Anagen is the active or growing phase. Catagen is a fairly short phase of the natural hair cycle during which hairs begin to break down. Telogen is the resting phase. The hairs that are shed daily are often in the resting or late phase in the hair cycle. Normally, about 10% of the scalp hairs are in the resting or telogen phase at any time. These hairs are not growing and are getting prepared for cyclic shedding.

In general, most hair loss is not associated with systemic or internal disease, nor is poor diet a frequent factor. Frequently, hair may simply thin as a result of predetermined genetic factors, family history, and the overall aging process. Many men and women may n...

Read the Hair Loss article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
Next »

Propecia User Reviews >>

Propecia

Hair Loss Slideshow Pictures

Hair and Scalp Slideshow Pictures

Take the Hair Loss Quiz!

font size

OVERDOSE

In clinical studies, single doses of finasteride up to 400 mg and multiple doses of finasteride up to 80 mg/day for three months did not result in adverse reactions. Until further experience is obtained, no specific treatment for an overdose with finasteride can be recommended.

Significant lethality was observed in male and female mice at single oral doses of 1500 mg/m² (500 mg/kg) and in female and male rats at single oral doses of 2360 mg/m² (400 mg/kg) and 5900 mg/m² (1000 mg/kg), respectively.

CONTRAINDICATIONS

PROPECIA is contraindicated in the following:

Pregnancy. Finasteride use is contraindicated in women when they are or may potentially be pregnant. Because of the ability of Type II 5α-reductase inhibitors to inhibit the conversion of testosterone to 5α-dihydrotestosterone (DHT), finasteride may cause abnormalities of the external genitalia of a male fetus of a pregnant woman who receives finasteride. If this drug is used during pregnancy, or if pregnancy occurs while taking this drug, the pregnant woman should be apprised of the potential hazard to the male fetus. [See WARNINGS AND PRECAUTIONS, Use In Specific Populations, HOW SUPPLIED/Storage and Handling and PATIENT INFORMATION.] In female rats, low doses of finasteride administered during pregnancy have produced abnormalities of the external genitalia in male offspring.
Hypersensitivity to any component of this medication.