April 27, 2017
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Propine Patient Information Including Side Effects

Brand Names: Propine

Generic Name: dipivefrin ophthalmic (Pronunciation: dye pi VEF rin)

What is dipivefrin ophthalmic (Propine)?

Dipivefrin reduces the amount of fluid in the eye, which decreases pressure inside the eye.

Dipivefrin ophthalmic is used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye).

Dipivefrin ophthalmic may also be used for other purposes not listed in this medication guide.

What are the possible side effects of dipivefrin ophthalmic (Propine)?

Stop using dipivefrin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • severe stinging or burning in your eyes;
  • fast or uneven heart rate; or
  • high blood pressure (severe headache, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath).

Less serious side effects may include:

  • burning, stinging, or itching of your eyes;
  • blurred vision;
  • redness of the eye or eyelid;
  • sensitivity to light;
  • eye pain; or
  • headache.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the Propine (dipivefrin) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about dipivefrin ophthalmic (Propine)?

You should not use this medication if you are allergic to dipivefrin, or if you have narrow-angle glaucoma.

Before using dipivefrin, tell your doctor if you are allergic to any drugs, or if you have high blood pressure or a history of cataract surgery.

Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using dipivefrin before putting your contact lenses in.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Side Effects Centers

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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