Propulsid (Cisapride (Removed from US Market)) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

Propulsid

Hiatal Hernia »

What is a hiatal hernia?

A hiatal hernia is an anatomical abnormality in which part of the stomach protrudes through the diaphragm and up into the chest. Although hiatal hernias are present in approximately 15% of the population, they are associated with symptoms in only a minority of those afflicted.

Normally, the esophagus or food tube passes down through the chest, crosses the diaphragm, and enters the abdomen through a hole in the diaphragm called the esophageal hiatus. Just below the diaphragm, the esophagus joins the stomach. In individuals with hiatal hernias, the opening of the esophageal hiatus (hiatal opening) is larger than normal, and a portion of the upper stomach slips up or passes (herniates) through the hiatus and into the chest. Although hiatal hernias are occasionally seen in infants where they probably have been present from birth, most hiatal hernias in adults are believed to have developed over many years....

Read the Hiatal Hernia article »

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Propulsid

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Propulsid Patient Information including If I Miss a Dose

What happens if I miss a dose (Propulsid)?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose (Propulsid)?

Seek emergency medical attention.

Symptoms of a cisapride overdose include nausea, vomiting, rumbling noises in the stomach, flatulence, diarrhea, urinary frequency, tremors, seizures, and weakness.

What should I avoid while taking cisapride (Propulsid)?

Do not take cisapride with any of the following drugs: antibiotics such as clarithromycin (Biaxin), erythromycin (Ery-Tab, E.E.S., E-Mycin, others), troleandomycin (TAO), and sparfloxacin (Zagam); antidepressants such as amitriptyline (Elavil), maprotiline (Ludiomil), and nefazodone (Serzone); antifungal medications such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); phenothiazines such as prochlorperazine (Compazine, others) and promethazine (Phenergan, others); antihistamines such as astemizole (Hismanal); blood pressure medications such as bepridil (Vascor); heart medications such as procainamide (Procan SR, Procanbid, Pronestyl) and quinidine (Quinidex, Quinaglute); and HIV medications such as indinavir (Crixivan) and ritonavir (Norvir). Taken with any of these drugs, cisapride may cause irregular heartbeats that could lead to death. This is not a complete list of drugs that may interact with cisapride and cause heart problems. Talk to your doctor or pharmacist before taking any other medications.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking cisapride.

Use other medications cautiously during treatment with cisapride to avoid harming yourself or others. Excessive drowsiness may result if benzodiazepines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril) are taken during cisapride therapy.

Do not consume grapefruit or grapefruit juice while taking cisapride. Grapefruit products may increase amount of cisapride available in your body, which could lead to dangerous side effects.

What other drugs will affect cisapride (Propulsid)?

The effects of cisapride may be decreased by drugs such as clidinium (Quarzan), dicyclomine (Bentyl), hyoscyamine (Levsin, Cystospaz, Anaspaz), belladonna (Donnatal), and propantheline (Pro-Banthine).

Cimetidine (Tagamet, Tagamet HB) may increase the level of cisapride in your body. Talk to your doctor before taking cimetidine during treatment with cisapride.

Warfarin (Coumadin) may have increased effects during treatment with cisapride. This could lead to bleeding. Your doctor may need to make adjustments to your warfarin dosage.

Use other medications cautiously during treatment with cisapride to avoid harming yourself or others. Excessive drowsiness may result if benzodiazepines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), and temazepam (Restoril) are taken during cisapride therapy.

Drugs other than those listed here may also interact with cisapride. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

Your pharmacist has more information about cisapride written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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