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Propylthiouracil

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Propylthiouracil

Propylthiouracil

INDICATIONS

Propylthiouracil (propylthiouracil (propylthiouracil (propylthiouracil tablet) tablet) tablet) is indicated in the medical treatment of hyperthyroidism. Long-term therapy may lead to remission of the disease. Propylthiouracil (propylthiouracil (propylthiouracil (propylthiouracil tablet) tablet) tablet) may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy of radioactive iodine therapy. Propylthiouracil (propylthiouracil (propylthiouracil (propylthiouracil tablet) tablet) tablet) is also used when thyroidectomy is contraindicated or not advisable.

DOSAGE AND ADMINISTRATION

Propylthiouracil (propylthiouracil (propylthiouracil (propylthiouracil tablet) tablet) tablet) is administered orally. The total daily dosage is usually given in 3 equal doses at approximately 8-hour intervals.

Adults

The initial dose is 300 mg daily. In patients with severe hyper-thyroidism, very large goiters, or both, the beginning dosage usually should be 400 mg daily, an occasional patient will require 600 to 900 mg/day initially. The usual maintenance dosage is 100 to 150 mg daily.

Pediatric Patients

For children 6 to 10 years of age, the initial dosage is 50 to 150 mg daily. For pediatric patients 10 years and over, the initial dosage is 150 to 300 mg daily. The maintenance dosage is determined by the response of the patient.

HOW SUPPLIED

Propylthiouracil (propylthiouracil (propylthiouracil (propylthiouracil tablet) tablet) tablet) Tablets, USP, 50 mg: White, scored tablet, imprinted “West-ward 480”.

Bottles of 100 tablets.

Bottles of 1000 tablets.

Unit Dose Boxes of 100 tablets.

Store at 20-25°C (68-77°F) [See USP Controlled Room Temperature]. Protect from light and moisture.

Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.

Manufactured By: West-ward Pharmaceutical Corp., Eatontown, NJ 07724. Revised November 2002

Last reviewed on RxList: 1/25/2010
This monograph has been modified to include the generic and brand name in many instances.

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