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"Sometimes the juice ain't worth the squeeze... especially when combining grapefruit with medicines.

While it can be part of a balanced and nutritious diet, grapefruit can have serious consequences when taken with certain medications. Cu"...



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ProQuad (measles mumps rubella varicella vaccine live) should not be administered

  • to individuals with a history of anaphylactic reactions to neomycin. If vaccination with ProQuad (measles mumps rubella varicella vaccine live) is medically necessary for such individuals, they are advised to consult an allergist or immunologist and should receive ProQuad (measles mumps rubella varicella vaccine live) only in settings where anaphylactic reactions can be appropriately managed.
  • to individuals with a history of hypersensitivity to gelatin or any other component of the vaccine (see WARNINGS for exceptions).
  • to individuals with blood dyscrasias, leukemia, lymphomas of any type, or other malignant neoplasms affecting the bone marrow or lymphatic system.
  • to individuals on immunosuppressive therapy (including high-dose systemic corticosteroids); ProQuad (measles mumps rubella varicella vaccine live) may be used by individuals who are receiving topical corticosteroids or low-dose corticosteroids, as are commonly used for asthma prophylaxis or in patients who are receiving corticosteroids as replacement therapy, e.g., for Addison's disease.
  • to individuals with primary and acquired immunodeficiency states, including AIDS or other clinical manifestations of infection with human immunodeficiency viruses; cellular immune deficiencies; and hypogammaglobulinemic and dysgammaglobulinemic states. Measles inclusion body encephalitis, pneumonitis, and death as a direct consequence of disseminated measles vaccine virus infection have been reported in severely immunocompromised individuals inadvertently vaccinated with measles-containing vaccine. In addition, disseminated varicella vaccine virus infection has been reported in children with underlying immunodeficiency disorders who were inadvertently vaccinated with a varicella-containing vaccine.10
  • to individuals with a family history of congenital or hereditary immunodeficiency, unless the immune competence of the potential vaccine recipient is demonstrated.
  • to individuals with active untreated tuberculosis.
  • to individuals with an active febrile illness with fever > 101.3°F ( > 38.5°C).
  • to individuals who are pregnant; the possible effects of the vaccine on fetal development are unknown at this time (see PRECAUTIONS, Pregnancy).

Last reviewed on RxList: 2/14/2008
This monograph has been modified to include the generic and brand name in many instances.


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