(ciprofloxacin) Extended-Release Tablets, 500 mg*
*present as 582 mg of ciprofloxacin hydrochloride monohydrate
- Patient Information:
Details with Side Effects
TENDONITIS AND TENDON RUPTURE
Fluoroquinolones, including Proquin XR (ciprofloxacin hcl) , are associated with an increased risk of tendinitis and tendon rupture in all ages. The risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart and lung transplant recipients [See WARNINGS AND PRECAUTIONS]. Fluroquinolones, including Proquin XR (ciprofloxacin hcl) , may exacerbate muscle weakness in persons with myasthenia gravis. Avoid Proquin XR (ciprofloxacin hcl) in patients with known history of myasthenia gravis (See WARNINGS).
Proquin XR (ciprofloxacin hydrochloride monohydrate) extended-release tablets contain 582 mg of ciprofloxacin hydrochloride monohydrate, a synthetic broad-spectrum fluoroquinolone antimicrobial agent for oral administration, which is equivalent to 500 mg of ciprofloxacin.
Ciprofloxacin hydrochloride monohydrate is 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1piperazinyl)-3-quinolinecarboxylic acid hydrochloride monohydrate. The molecular weight of the ciprofloxacin hydrochloride monohydrate is 385.82. It is a faintly yellowish to light yellow crystalline substance and its chemical structure is as follows:
Proquin XR is available as 500 mg (ciprofloxacin hydrochloride monohydrate equivalent) tablets, utilizing AcuForm® delivery technology. Proquin XR (ciprofloxacin hcl) tablets are blue film-coated and oval-shaped. The inactive ingredients are povidone, magnesium stearate, polyethylene oxide, and film coating (Opadry® Blue).
What are the possible side effects of ciprofloxacin (Cipro, Cipro XR, Proquin XR)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using ciprofloxacin and call your doctor at once if you have a serious side effect such as:
- severe dizziness, fainting, fast or pounding heartbeats;
- sudden pain, snapping or popping sound, bruising, swelling, tenderness, stiffness, or loss of movement in any of your joints;
- diarrhea that is watery or bloody;
- confusion, hallucinations, depression, unusual...
What are the precautions when taking ciprofloxacin hcl (Proquin XR)?
Before taking ciprofloxacin, tell your doctor or pharmacist if you are allergic to it; or to other quinolone antibiotics such as norfloxacin, gemifloxacin, levofloxacin, moxifloxacin, or ofloxacin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart problems (e.g., recent heart attack), joint/tendon problems (e.g., tendonitis, bursitis), kidney disease, liver disease, myasthenia gravis, nervous system disorder (e.g., peripheral neuropathy), seizure disorder, conditions that increase your risk of seizures (e.g., brain/head injury, brain tumors,...
Last reviewed on RxList: 4/24/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Proquin XR Information
Proquin XR - User Reviews
Proquin XR User Reviews
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