May 23, 2017
Recommended Topic Related To:

Proquin XR

"April 29, 2015 -- If you've ever had one (or a dozen) urinary tract infections, you might not be surprised to learn that they're the most common bacterial infections in the United States.

What you might not know is that doctors are running "...


Proquin XR

Proquin® XR
(ciprofloxacin) Extended-Release Tablets, 500 mg*

*present as 582 mg of ciprofloxacin hydrochloride monohydrate



Fluoroquinolones, including Proquin XR (ciprofloxacin hcl) , are associated with an increased risk of tendinitis and tendon rupture in all ages. The risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart and lung transplant recipients [See WARNINGS AND PRECAUTIONS]. Fluroquinolones, including Proquin XR (ciprofloxacin hcl) , may exacerbate muscle weakness in persons with myasthenia gravis. Avoid Proquin XR (ciprofloxacin hcl) in patients with known history of myasthenia gravis (See WARNINGS).


Proquin XR (ciprofloxacin hydrochloride monohydrate) extended-release tablets contain 582 mg of ciprofloxacin hydrochloride monohydrate, a synthetic broad-spectrum fluoroquinolone antimicrobial agent for oral administration, which is equivalent to 500 mg of ciprofloxacin.

Ciprofloxacin hydrochloride monohydrate is 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1piperazinyl)-3-quinolinecarboxylic acid hydrochloride monohydrate. The molecular weight of the ciprofloxacin hydrochloride monohydrate is 385.82. It is a faintly yellowish to light yellow crystalline substance and its chemical structure is as follows:

Proquin® XR (ciprofloxacin) Structural Formula Illustration

Proquin XR is available as 500 mg (ciprofloxacin hydrochloride monohydrate equivalent) tablets, utilizing AcuForm® delivery technology. Proquin XR (ciprofloxacin hcl) tablets are blue film-coated and oval-shaped. The inactive ingredients are povidone, magnesium stearate, polyethylene oxide, and film coating (Opadry® Blue).

What are the possible side effects of ciprofloxacin (Cipro, Cipro XR, Proquin XR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using ciprofloxacin and call your doctor at once if you have a serious side effect such as:

  • severe dizziness, fainting, fast or pounding heartbeats;
  • sudden pain, snapping or popping sound, bruising, swelling, tenderness, stiffness, or loss of movement in any of your joints;
  • diarrhea that is watery or bloody;
  • confusion, hallucinations, depression, unusual...

Read All Potential Side Effects and See Pictures of Proquin XR »

What are the precautions when taking ciprofloxacin hcl (Proquin XR)?

Consult your...

Read All Potential Precautions of Proquin XR »

Last reviewed on RxList: 12/8/2016
This monograph has been modified to include the generic and brand name in many instances.

Proquin XR - User Reviews

Proquin XR User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Proquin XR sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Women's Health

Find out what women really need.