Proquin XR (Ciprofloxacin Hcl) Drug Information: Overdosage and Contraindications

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May 27, 2012

Proquin XR

Diarrhea »

Diarrhea facts

Diarrhea is an increase in the frequency of bowel movements, an increase in the looseness of stool or both.
Diarrhea is caused by increased secretion of fluid into the intestine, reduced absorption of fluid from the intestine or rapid passage of stool through the intestine.
Diarrhea can be defined absolutely or relatively. Absolute diarrhea is defined as more than five bowel movements a day or liquid stools. Relative diarrhea is defined as an increase in the number of bowel movements per day or an increase in the looseness of stools compared with an individual's usual bowel habit.
Diarrhea may be either acute or chronic, and each has different causes and treatments.
Complications of diarrhea include dehydration, electrolytes (mineral) abnormalities, and irritation of the anus.
Dehydration can be treated with oral ...

Read the Diarrhea article »

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OVERDOSE

Only a small amount of ciprofloxacin ( < 10%) is removed from the body after hemodialysis or peritoneal dialysis.

In the event of an acute overdosage, the stomach should be emptied by inducing vomiting or by gastric lavage. The patient should be carefully observed and given supportive treatment. Adequate hydration must be maintained.

Serious adverse effects were not observed in rats receiving single oral doses of ciprofloxacin as high as 2,000 mg/kg.

CONTRAINDICATIONS

Proquin XR (ciprofloxacin hcl) is contraindicated in persons with a known hypersensitivity to ciprofloxacin or other quinolone antibacterials [see WARNINGS AND PRECAUTIONS].

Last reviewed on RxList: 4/19/2011
This monograph has been modified to include the generic and brand name in many instances.