July 24, 2016
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Prosed DS

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Prosed DS

Prosed DS Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 2/15/2016

Prosed DS (methenamine, phenyl salicylate, methylene blue, benzoic acid, hyoscyamine sulfate) is a combination of two antibiotics, an analgesic, an antiseptic, and an antispasmodic used to treat discomfort of the lower urinary tract, and in the treatment of cystitis, urethritis, and trigonitis. Prosed DS is available in generic form. Common side effects of Prosed DS include rapid pulse, flushing, blurred vision, dizziness, shortness of breath, difficulty breathing, dry mouth, nausea, vomiting, difficulty urinating or urinary retention.

The recommended dosage of Prosed DS is one tablet taken orally 4 times per day followed by liberal fluid intake. Urinary alkalizer, thiazide diuretics, antimuscarinics, antacids, antidiarrheals, antimyasthenics, and MAOIs may interact with Prosed DS. Tell your doctor all medications you take. If you are pregnant take Prosed DS only if clearly needed. Exercise caution if you are breastfeeding and taking Prosed DS.

Our Prosed DS (methenamine, phenyl salicylate, methylene blue, benzoic acid, hyoscyamine sulfate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Prosed DS FDA Prescribing Information: Side Effects
(Adverse Reactions)


Cardiovascular - rapid pulse, flushing

Central Nervous System - blurred vision, dizziness

Respiratory - shortness of breath or troubled breathing

Genitourinary - difficult micturition, acute urinary retention

Gastrointestinal - dry mouth, nausea/vomiting

Drug Abuse And Dependence

A dependence on the use of PROSED®/DS has not been reported and due to the nature of its ingredients, abuse of PROSED®/DS is not expected.

Read the entire FDA prescribing information for Prosed DS (Methenamine, Salicylate, Methylene Blue, Benzoic Acid Atropine and Hyoscyamine)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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