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In this Article

• What is neostigmine (Prostigmin)?
• What are the possible side effects of neostigmine (Prostigmin)?
• What is the most important information I should know about neostigmine (Prostigmin)?
• What should I discuss with my health care provider before taking neostigmine (Prostigmin)?
• How should I take neostigmine (Prostigmin)?
• What happens if I miss a dose (Prostigmin)?
• What happens if I overdose (Prostigmin)?
• What should I avoid while taking neostigmine (Prostigmin)?
• What other drugs will affect neostigmine (Prostigmin)?
• Where can I get more information?

What should I discuss with my health care provider before taking neostigmine (Prostigmin)?

Do not use neostigmine if you have:

• a serious stomach condition called peritonitis; or
• a bladder or bowel obstruction.

Before using neostigmine, tell your doctor if you have:

• asthma;
• epilepsy or other seizure disorder;
• a heart rhythm disorder;
• problems with your blood vessels or circulation;
• overactive thyroid; or
• a stomach ulcer.

If you have any of these conditions, you may not be able to use neostigmine, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether neostigmine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take neostigmine (Prostigmin)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

The amount and timing of this medicine is extremely important to the success of your treatment. Carefully follow your doctor's instructions about how much medicine to take and when to take it.

Your doctor may occasionally change your dose to make sure you get the best results from this medication. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking neostigmine. You may need to stop using the medicine for a short time.

Store neostigmine at room temperature away from moisture and heat.