June 27, 2016
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Prostin E2

"Short-term (usually less than 48 hours) use of magnesium sulfate in obstetric care is appropriate for certain conditions and durations of treatment, according to a committee opinion from the American College of Obstetricians and Gynecologists and"...

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Prostin E2




Indications
Dosage
How Supplied

INDICATIONS

  • PROSTIN E2 Vaginal Suppository is indicated for the termination of pregnancy from the 12th through the 20th gestational week as calculated from the first day of the last normal menstrual period.
  • PROSTIN E2 is also indicated for evacuation of the uterine contents in the management of missed abortion or intrauterine fetal death up to 28 weeks of gestational age as calculated from the first day of the last normal menstrual period.
  • PROSTIN E2 is indicated in the management of nonmetastatic gestational trophoblastic disease (benign hydatidiform mole).

DOSAGE AND ADMINISTRATION

STORE IN A FREEZER NOT ABOVE -20°C (-4°F) BUT BRING TO ROOM TEMPERATURE JUST PRIOR TO USE.

REMOVE FOIL BEFORE USE.

A suppository containing 20 mg of dinoprostone should be inserted high into the vagina. The patient should remain in the supine position for ten minutes following insertion.

Additional intravaginal administration of each subsequent suppository should be at 3- to 5-hour intervals until abortion occurs. Within the above recommended intervals administration time should be determined by abortifacient progress, uterine contractility response, and by patient tolerance. Continuous administration of the drug for more than 2 days is not recommended.

HOW SUPPLIED

PROSTIN E2 Vaginal Suppositories are available in foil strips of 5 individually sealed suppositories, NDC 0009-0827-03. Each suppository contains 20 mg of dinoprostone in a mixture of glycerides of fatty acids.

STORE IN A FREEZER NOT ABOVE -20°C (-4°F).

This product's label may have been updated. For current full prescribing information, please visit www.pfizer.com

Distributed by: Pharmacia & Upjohn Co., Division of Pfizer Inc., New York NY, 10017. Revised: Dec 2014

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 6/13/2016

Indications
Dosage
How Supplied

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