"Fast on the heels of their first uterus transplant, surgeons and clinicians at the Cleveland Clinic in Ohio say at least one additional woman is ready to receive a new uterus, and several more are close to reaching that goal.
The most frequent adverse reactions observed with the use of dinoprostone for abortion are related to its contractile effect on smooth muscle.
In the patients studied, approximately two-thirds experienced vomiting, one-half temperature elevations, two-fifths diarrhea, one-third some nausea, one-tenth headache, and one-tenth shivering and chills.
In addition, approximately one-tenth of the patients studied exhibited transient diastolic blood pressure decreases of greater than 20 mmHg.
It is not known whether these events were related to the administration of dinoprostone.
Adverse effects in decreasing order of their frequency, observed with the use of dinoprostone, not all of which are clearly drug related include:
Chills or shivering
Joint inflammation or pain new or exacerbated
Flushing or hot flashes
Syncope or fainting sensation
Vaginitis or vulvitis
Muscular cramp or pain
Tightness in chest
|Nocturnal leg cramps
Read the Prostin E2 (dinoprostone vaginal suppository) Side Effects Center for a complete guide to possible side effects
PROSTIN E2 may augment the activity of other oxytocic drugs. Concomitant use with other oxytocic agents is not recommended.
Read the Prostin E2 Drug Interactions Center for a complete guide to possible interactions
Last reviewed on RxList: 6/13/2016
Additional Prostin E2 Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Parenting and Pregnancy
Get tips for baby and you.