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Protonix

Overview of Heartburn

The esophagus is a tube that connects the mouth to the stomach. It is made of muscles that work to push food toward the stomach in rhythmic waves. Once in the stomach, food is prevented from refluxing (moving back into the esophagus), by a special area of circular muscle located at the junction of the esophagus and stomach, called the lower esophageal sphincter (LES). A pressure difference across the diaphragm, the flat muscle that separates the chest from the abdomen, also tends to keep stomach contents in the stomach.

The stomach combines food, acids, and enzymes together to begin digestion. There are special protective cells that line the stomach to prevent the acid from causing inflammation. The esophagus does not have this same protection; if stomach products reflux back into the esophagus, they can cause inflammation to the lining.

Heartburn Causes

Heartburn is actually a symptom of G...

Protonix

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Protonix Drug Center

Medical Editor: Melissa Conrad Stöppler, MD

Protonix (pantoprazole) is a medication in the proton-pump inhibitor (PPI) class used to treat esophagitis associated with gastroesophageal reflux disease (GERD). Protonix is supplied as delayed-release granules in packets for preparation of oral suspensions or as delayed-release tablets. Common side effects of Protonix include headache, diarrhea, nausea, and abdominal pain.

Long-term treatment with Protonix may make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. In long-term rodent studies, pantoprazole was carcinogenic and caused rare types of gastrointestinal tumors. The relevance of these findings to tumor development in humans is unknown. Animal studies showed no harm during pregnancy; however there are no adequate and well-controlled studies in pregnant women, and this drug should be used during pregnancy only if clearly needed. Pantoprazole and its metabolites are excreted in the milk of rats. Based on the potential for tumorigenicity shown for pantoprazole in rodent carcinogenicity studies, a decision should be made whether to discontinue nursing or to discontinue the drug.

Our Protonix Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements and disease and conditions.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Protonix Prescribing Information: Indications & Dosage

PROTONIX (pantoprazole sodium) Structural Formula Illustration

PROTONIX For Delayed-Release Oral Suspension and PROTONIX Delayed-Release Tablets are indicated for:

Short-Term Treatment of Erosive Esophagitis Associated With Gastroesophageal Reflux Disease (GERD)

PROTONIX is indicated in adults and pediatric patients five years of age and older for the short-term treatment (up to 8 weeks) in the healing and symptomatic relief of erosive esophagitis. For those adult patients who have not healed after 8 weeks of treatment, an additional 8-week course of PROTONIX may be considered. Safety of treatment beyond 8 weeks in pediatric ...

Read the complete drug monograph for Protonix »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Protonix Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely to occur, such as:

  • nausea, vomiting;
  • gas, stomach pain;
  • diarrhea; or
  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I sh...

Read the complete patient information for Protonix »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Protonix Consumer Information: Uses

Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux). It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).

OTHER USES: This section contains uses of this drug that are not listed in the approved US profess...

Read the complete consumer information for Protonix »

What is Protonix Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Protonix - User Reviews

Protonix User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Protonix sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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