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The recommended dosage of up to 0.30 mg/kg (approximately 0.90 IU/kg) of body weight weekly should not be exceeded due to the potential risk of known effects of excess human growth hormone.

Protropin^® (somatrem for injection) should not be used in subjects with closed epiphyses.

Protropin (somatrem) should not be used in patients with active neoplasia. Growth hormone therapy should be discontinued if evidence of neoplasia develops.

Protropin (somatrem) , when reconstituted with Bacteriostatic Water for Injection, USP (benzyl alcohol preserved) should not be used in patients with a known sensitivity to benzyl alcohol.

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.