"On December 21, the U.S. Food and Drug Administration approved Uptravi (selexipag) tablets to treat adults with pulmonary arterial hypertension (PAH), a chronic, progressive, and debilitating rare lung disease that can lead to death or the need f"...
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
METHACHOLINE - INHALATION
COMMON BRAND NAME(S): Provocholine
WARNING: This medication must be used in a hospital or clinic setting under close medical supervision. It is only to be used for testing (challenge test) and should not be used to treat any conditions.
Emergency equipment and medications must be available to reverse the effects of methacholine if you experience any breathing difficulties during or after the test.
This drug is not recommended for use if you already have asthma, wheezing, or poor lung function test results before this challenge test.
USES: Methacholine is used as a test to determine whether you may have asthma. It is a cholinergic drug that causes wheezing and shortness of breath.
HOW TO USE: This medication is to be inhaled only with a special breathing device (nebulizer) under the direct supervision of a health care professional in a hospital or clinic setting. Do not take this medication by mouth or by injection.
This product must be diluted before being inhaled. Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. Use a filter when putting this medication into the nebulizer.
Tell the health care professional if you develop any trouble breathing at any time during the test.
The dosage is based on your medical condition and response to treatment.
Additional Provocholine Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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