"The U.S. Food and Drug Administration yesterday approved Ruconest, the first recombinant C1-Esterase Inhibitor product for the treatment of acute attacks in adult and adolescent patients with hereditary angioedema (HAE).
Pulmozyme (dornase alfa) must be stored in the refrigerator at 2-8°C (36-46°F) and protected from strong light. It should be kept refrigerated during transport and should not be exposed to room temperatures for a total time of 24 hours. The solution should be discarded if it is cloudy or discolored. Pulmozyme (dornase alfa) contains no preservative and, once opened, the entire contents of the ampule must be used or discarded. Patients should be instructed in the proper use and maintenance of the nebulizer and compressor system used in its delivery.
Pulmozyme (dornase alfa) should not be diluted or mixed with other drugs in the nebulizer. Mixing of Pulmozyme (dornase alfa) with other drugs could lead to adverse physicochemical and/or functional changes in Pulmozyme (dornase alfa) or the admixed compound.
Last reviewed on RxList: 12/16/2008
This monograph has been modified to include the generic and brand name in many instances.
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