"The U.S. Food and Drug Administration today approved Iclusig (ponatinib) to treat adults with chronic myeloid leukemia (CML) and Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL), two rare blood and bone marrow diseases."...
Purinethol Consumer (continued)
This drug should not be used within 2 weeks of receiving a live vaccine (e.g., flu, measles, mumps, polio). Before taking this medication, tell your doctor of any planned or recently received vaccines. (See also Precautions section.)
This drug should not be used with the following medication because a very serious interaction may occur: febuxostat.
If you are currently using the medication listed above, tell your doctor or pharmacist before starting mercaptopurine.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: aminosalicylates (e.g., olsalazine, mesalazine, sulfasalazine), aspirin, "blood thinners" (e.g., warfarin), drugs that may affect the bone marrow (e.g., trimethoprim/sulfamethoxazole, other cancer chemotherapies), drugs that may affect the liver (e.g., amiodarone, erythromycin).
Before using this medication, tell your doctor or pharmacist if you are taking allopurinol. The dose of mercaptopurine may need to be decreased to avoid severe side effects.
If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.
This product can affect the results of certain lab tests (e.g., uric acid), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
Mercaptopurine is very similar to azathioprine. Do not use medications containing azathioprine while using mercaptopurine.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: sudden or severe nausea/vomiting, sudden/severe diarrhea, dark urine, severe abdominal pain, yellowing eyes/skin.
NOTES: Do not share this medication with others.
Laboratory and/or medical tests (e.g., complete blood count, liver function tests) should be performed periodically to monitor your progress or check for side effects. Keep all medical/lab appointments. Consult your doctor for more details.
MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).
Information last revised June 2014. Copyright(c) 2014 First Databank, Inc.
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