"The U.S. Food and Drug Administration today approved Zydelig (idelalisib) to treat patients with three types of blood cancers.
Zydelig is being granted traditional approval to treat patients whose chronic lymphocytic leukemia (CLL) has retu"...
Purinethol Patient Information including If I Miss a Dose
In this Article
- What is mercaptopurine (Purinethol)?
- What are the possible side effects of mercaptopurine (Purinethol)?
- What is the most important information I should know about mercaptopurine (Purinethol)?
- What should I discuss with my healthcare provider before taking mercaptopurine (Purinethol)?
- How should I take mercaptopurine (Purinethol)?
- What happens if I miss a dose (Purinethol)?
- What happens if I overdose (Purinethol)?
- What should I avoid while taking mercaptopurine (Purinethol)?
- What other drugs will affect mercaptopurine (Purinethol)?
- Where can I get more information?
What happens if I miss a dose (Purinethol)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Purinethol)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include some of the serious side effects listed in this medication guide.
What should I avoid while taking mercaptopurine (Purinethol)?
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Do not receive a "live" vaccine while using mercaptopurine. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), oral polio, rotavirus, typhoid, varicella (chickenpox), H1N1 influenza, and nasal flu vaccine.
What other drugs will affect mercaptopurine (Purinethol)?
Tell your doctor about all other cancer treatments you are receiving. Also tell your doctor about all other medicines you use, especially:
- acetaminophen (Tylenol);
- allopurinol (Zyloprim, Aloprim, Lopurin);
- auranofin (Ridaura);
- azathioprine (Azasan, Imuran);
- cyclosporine (Gengraf, Neoral, Sandimmune);
- methotrexate (Rheumatrex, Trexall);
- olsalazine (Dipentum), mesalamine (Pentasa, Rowasa, Asacol), or sulfasalazine (Azulfidine);
- sulfamethoxazole and trimethoprim (Bactrim, Septra, Sulfatrim, SMX-TMP, and others);
- thioguanine (Tabloid);
- birth control pills or hormone replacement therapy;
- a blood thinner such as warfarin (Coumadin, Jantoven);
- tuberculosis medications;
- cholesterol medications such as niacin (Advicor, Niaspan, Niacor, Simcor, Slo Niacin, and others), atorvastatin (Lipitor, Caduet), simvastatin (Zocor, Simcor, Vytorin), lovastatin (Mevacor, Altoprev, Advicor), pravastatin (Pravachol), and others;
- an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others; or
- an ACE inhibitor such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others;
- an antibiotic such as dapsone, erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or rifampin (Rifater, Rifadin, Rifamate);
- antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);
- seizure medications such as carbamazepine (Carbatrol, Tegretol), phenytoin (Dilantin), felbamate (Felbatol), valproic acid (Depakene); or
- HIV/AIDS medications such as abacavir/lamivudine/zidovudine (Trizivir), lamivudine (Combivir, Epivir), nevirapine (Viramune), tenofovir (Viread), or zidovudine (Retrovir);
This list is not complete and other drugs may interact with mercaptopurine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your doctor or pharmacist can provide more information about mercaptopurine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2013 Cerner Multum, Inc. Version: 8.01. Revision date: 5/10/2011.
Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link.
Additional Purinethol Information
- Purinethol Drug Interactions Center: mercaptopurine oral
- Purinethol Side Effects Center
- Purinethol Overview including Precautions
- Purinethol FDA Approved Prescribing Information including Dosage
Purinethol - User Reviews
Purinethol User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.