In this Article

• What is pyrazinamide ?
• What are the possible side effects of pyrazinamide ?
• What is the most important information I should know about pyrazinamide ?
• Who should not take pyrazinamide ?
• How should I take pyrazinamide ?
• What happens if I miss a dose ?
• What happens if I overdose ?
• What should I avoid while taking pyrazinamide ?
• What other drugs will affect pyrazinamide ?
• Where can I get more information?

Who should not take pyrazinamide ?

Before taking pyrazinamide, tell your doctor if you have

• ever had an allergic reaction to pyrazinamide,
• liver disease,
• gout,
• kidney disease, or
• diabetes mellitus.

You may not be able to take pyrazinamide, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Pyrazinamide is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.

Pyrazinamide passes into breast milk and may affect a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take pyrazinamide ?

Take pyrazinamide exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 ounces) of water.

Take all of the pyrazinamide that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

Pyrazinamide is usually combined with one or more other tuberculosis medicines.

Store this medication at room temperature away from moisture and heat.