August 24, 2016

Pyruvate

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How does Pyruvate work?

Pyruvate might contribute to weight loss by increasing the breakdown of fat.

In addition, pyruvic acid seems to cause the outer layer of skin cells to slough off, which accounts for its use in reversing aging due to exposure to the sun.

Are there safety concerns?

Pyruvate is POSSIBLY SAFE when taken by mouth or inhaled using a nebulizer for up to six weeks. Side effects such as stomach upset, gas, bloating, and diarrhea can occur when large amounts are taken.

Pyruvic acid facial peels are POSSIBLY SAFE when applied by a healthcare professional. It can cause severe skin burning and should be applied only to small patches of skin at a time.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking pyruvate if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

A heart condition called cardiomyopathy: One death was associated with intravenous use in a child who had cardiomyopathy.

Diarrhea: Taking high amounts of pyruvate by mouth might worsen diarrhea.

Irritable bowel syndrome (IBS): Taking high amounts of pyruvate by mouth might worsen symptoms of IBS.

Dosing considerations for Pyruvate.

The following doses have been studied in scientific research:

APPLIED TO THE SKIN:
  • For aging skin: A 50% pyruvic acid peel applied once weekly for 4 weeks.

Therapeutic Research Faculty copyright

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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