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Overdosage with QUADRAMET® (samarium sm 153 lexidronam) has not been reported. An antidote for QUADRAMET® (samarium sm 153 lexidronam) overdosage is not known. The anticipated complications of overdosage would likely be secondary to bone marrow suppression from the radioactivity of 153Sm, or secondary to hypocalcemia and cardiac arrhythmias related to the EDTMP.
QUADRAMET® (samarium sm 153 lexidronam) is contraindicated in patients who have known hypersensitivity to EDTMP or similar phosphonate compounds.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 10/8/2008
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