Quinidex (Quinidine) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

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Atrial Fibrillation »

What is atrial fibrillation?

Atrial fibrillation (AF) is the most common, abnormal rhythm of the heart.

The heart contracts (beats) and pumps blood with a regular rhythm, for example, at a rate of 60 beats per minute there is a beat every second. The heart may beat faster or slower with a shorter or longer interval between beats, but at any one rate the interval between beats is constant. This regular rhythm occurs as a result of regular electrical discharges (currents) that travel through the heart and cause the muscle of the heart to contract. In atrial fibrillation, the electrical discharges are irregular and rapid and, as a result, the heart beats irregularly and, usually, rapidly.

Atrial fibrillation is common; half a million new cases are diagnosed yearly in the U.S., and billions of dollars are spent annually on its diagnosis and treatment.

What causes atrial fibrillation?

Normal function of the he...

Read the Atrial Fibrillation article »

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Quinidex Patient Information including If I Miss a Dose

What happens if I miss a dose (Quinidex)?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication. A double dose could be dangerous.

What happens if I overdose (Quinidex)?

Seek emergency medical attention.

Symptoms of a quinidine overdose include confusion, tiredness, seizures, difficulty breathing, fainting, a rapid heartbeat, and coma.

What should I avoid while taking quinidine (Quinidex)?

Grapefruit and grapefruit juice may interact with quinidine. The interaction could lead to potentially adverse effects. You should discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

What other drugs will affect quinidine (Quinidex)?

Before taking quinidine, tell your doctor if you are taking any of the following medicines:

pimozide (Orap);
itraconazole (Sporanox);
ziprasidone (Geodon);
voriconazole (VFEND);
thioridazine (Mellaril) or mesoridazine (Serentil);
ritonavir (Norvir);
dolasetron (Anzemet);
digoxin (Lanoxin);
warfarin (Coumadin);
erythromycin (E-Mycin, Eryc, E.E.S., others);
sparfloxacin (Zagam), levofloxacin (Levaquin), grepafloxacin (Raxar), gatifloxacin (Tequin);
another medicine to treat irregular heartbeats such as bepridil (Vascor), dofetilide (Tikosyn), procainamide (Procan SR, Procanbid, Pronestyl), disopyramide (Norpace), and others;
a beta-blocker such as atenolol (Tenormin), metoprolol (Lopressor), propranolol (Inderal), and others;
a tricyclic antidepressant such as amitriptyline (Elavil), doxepin (Sinequan), clomipramine (Anafranil), imipramine (Tofranil), others; or
a phenothiazine such as chlorpromazine (Thorazine), promethazine (Phenergan, Promethegan), prochlorperazine (Compazine), and others.

You may not be able to take quinidine, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Many drugs other than those listed here can interact with quinidine, resulting in dangerous side effects and/or decreased effectiveness. Do not take any other prescription or over-the-counter medications, including herbal products, during treatment with quinidine without first talking to your doctor or pharmacist.

Where can I get more information?

Your pharmacist has more information about quinidine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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