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Quinidine is an antimalarial schizonticide and an antiarrhythmic agent with Class Ia activity; it is the d-isomer of quinine, and its molecular weight is 324.43. Quinidine gluconate is the gluconate salt of quinidine; its chemical name is cinchonan-9-ol, 6'-methoxy-, (9S)-, mono-D-gluconate. The structural formula is represented below:
Quinidine gluconate contains 62.3% of the anhydrous quinidine alkaloid, whereas quinidine sulfate contains 82.86%. In prescribing Quinidine Gluconate Extended-release Tablets, this factor should be considered.
Each tablet, for oral administration, contains 324 mg of quinidine gluconate (202 mg of quinidine base) in a matrix to provide extended-release.
Quinidine Gluconate Extended-release Tablets contain the following inactive ingredients: carnauba wax, ethylcellulose, magnesium stearate and povidone.
This product meets USP Drug Release Test 1.
Last reviewed on RxList: 10/7/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Quinidine Gluconate Information
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