Palpitations are unpleasant sensations of irregular and/or forceful beating of the heart. Some persons with palpitations have no heart disease or abnormal heart rhythms and the reasons for their palpitations are unknown. In others, palpitations result from abnormal heart rhythms (arrhythmias).
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QUINIDINE GLUCONATE
(quinidine gluconate (quinidine gluconate (quinidine gluconate injection) injection) ) Injection
Quinidine is an antimalarial schizonticide and an antiarrhythmic agent with class 1a activity; it is the d–isomer of quinine and its molecular weight is 324.43. Quinidine gluconate (quinidine gluconate (quinidine gluconate injection) injection) is the gluconate salt of quinidine; its chemical name is cinchonan–9–ol, 6'– methoxy–, (9S)–, mono–D–gluconate; its structural formula is
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its empirical formula is C20H24N2O2•C6H12O7, and its molecular weight is 520.58, of which 62.3% is quinidine base.
Each vial of Quinidine Gluconate Injection contains 800 mg (1.5 mmol) of quinidine gluconate (quinidine gluconate (quinidine gluconate injection) injection) (500 mg of quinidine) in 10 mL of Sterile Water for Injection, 0.005% of edetate disodium, 0.25% phenol, and (as needed) D–gluconic acid d–lactone to adjust the pH.
Last reviewed on RxList: 5/21/2009
This monograph has been modified to include the generic and brand name in many instances.
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